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Featured Collection - CLEPIC 2025: Advances in Epigenetics, with a Focus on Clinical Progresses, Applied Technologies and Epitarget Therapeutics

Clinical Epigenetics and Epigenetics Communications are proud to publish the extended proceedings of CLEPIC 2025, an international conference covering the latest developments in the expansive field of epigenetics.

CLEPIC

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Save the Date for 

Clinical Epigenetics International Conference - CLEPIC 2025
Naples, Italy, June 11 – 13, 2025

More information at https://www.clepic.org


Welcoming words from Lucia Altucci and Marianne Rots, Editors in Chief of Clinical Epigenetics:

The need to meet and greet

Scientists need to meet to stay up-to-date within and beyond one’s own research field, to exchange and fuel new ideas, to keep inspired and to inspire others. We aim to offer you such platform by bringing together the editors, authors and readers of Clinical Epigenetics as well as the newly launched Epigenetics Communications. Moreover, we will invite industrial partners and public bodies, with a focus on training the next generation of multidisciplinary multi-epiomics scientists. This annual conference is devoted to fully exploiting the many applications of epigenetics in health and disease as well as in all kingdoms of life (biotech, crop breeding, etc.).

Looking forward to meeting and greeting many of you in a relaxed atmosphere full of state-of-the-art epigenetics!

Join us in marking DNA Day 2025!

To commemorate this important day, we are delighted to highlight two interesting new bog posts:

The Epigenetic Architects: How Polycomb Proteins Shape Zebrafish Heart and Pectoral Fin Development.

Neuer Inhalt (1)

By Pratiksha Kavade, University of Campania Luigi Vanvitelli

(a) Zebrafish pectoral fin development  (b) Effect of PRC1/PRC2 deficiency on pectoral fin development


New Tools for Screening for Enivronmentally Influenced Epigenetic Disease Risk Factors

By DavidNeuer Inhalt A. Skaar, NCSU

Figure 1 – Epigenetics as a mechanism for translating environmental exposures to outcomes

The 2025 Annual Congress of the European Association for Cancer Research (EACR 2025)

New Content Item

16-19 June 2025, Lisbon

Abstract deadline: 06 March 2025

Find out about confirmed speakers and more: here.


Call for Papers: Ecological Epigenetics: Unveiling Urban Impacts on the Epigenome

Epigenetics Communications is calling for submissions to our Collection on Ecological Epigenetics: Unveiling Urban Impacts on the Epigenome. This Collection will explore the ramifications of pollution on the epigenome with respect to long-term population health.

Call for Papers: Demonstrations of Transgenerational Epigenetic Inheritance in Various Model Systems

Epigenetics Communications is calling for submissions to our Collection on Demonstrations of Transgenerational Epigenetic Inheritance in Various Model Systems. This Collection aims to shed light on the mechanisms underlying transgenerational epigenetic inheritance and explore its potential evolutionary implications by presenting empirical evidence from diverse model systems.

Call for Papers: Epigenetic editing in/with/for society

Epigenetic editing holds the promise of substantive advancements in medicine, agriculture, and biotechnology by enabling precise molecular modifications inducing stable gene expression changes that do not alter the underlying DNA sequence. Epigenetics Communications is calling for submissions to our Collection on Epigenetic editing in/with/for society. This Collection aims to investigate the ethical, legal, and social aspects (ELSA) of epigenetic editing.

New thematic series: Multiscale chromatin dynamics

New Content ItemWe are proud to announce a new cross-journal thematic series between Epigenetics Communications and Clinical Epigenetics, guest edited by Pernette Verschure and Wim Vanden Berghe. The last few years have seen a wealth of knowledge on the role of epigenetic gene regulation in (patho-)physiological processes. New insights relate to the highly dynamic nature of epigenetic systems. Epigenetic regulatory proteins are in constant motion in the nucleus, exchanging between chromatin-bound and unbound states. In addition,  various layers of chromatin folding show defined dynamics. The causal relationship between these dynamics of chromatin and nuclear organization with gene activity and silencing is still an open question of great importance. Find out more about the scope here.

Find Best-Fit Journal for your article!

Choosing the right journal is essential for every author, and we are fully committed to collaborating across our prestigious epigenetics journals to assist you in this process. To facilitate an informed decision, we offer a concise overview of our three journals. For more detailed information on each one, simply click on the journal title below: 

New Content ItemClinical Epigenetics

Epigenetics & Chromatin 

Epigenetics Communications

Our dedicated Editors, with their extensive expertise in the field, will carefully evaluate your submission. If they believe that another journal within our network may better align with your research, they will propose a transfer during the peer-review process. This transfer will significantly expedite the handling of your submission, eliminating the need for additional peer-review rounds. We value your research and are here to support you every step of the way. Explore our options and make the most of our collaborative efforts to ensure your work reaches its full potential. 

Editorial Policy Regarding Submissions describing “Negative Outcome Studies”

Provided that the methodology is consistent and sound, and the research question brings added value to the field, we warmly welcome ‘negative results’ studies. Manuscripts to be considered include, but are not limited to, descriptions of:

  • (failed) attempts to reproduce previously published data
  • irreproducible data between two (collaborating) laboratories
  • failed, but technically solid, attempts to prove a scientific hypothesis

Manuscripts which will not be considered include:

  • bioinformatic analyses without a solid statistical approach
  • "stand alone" bioinformatic analyses without experimental proof

Editorial Policy Regarding Submissions Focusing on Non-coding RNAs or RNA Modifications

Since epigenetic regulation and associated aspects of transcription regulation are wide-spread and complex, Epigenetics Communications aims to focus on those aspects of ncRNA-induced epigenetic regulation that concern changes in chromatin organization. As such manuscripts on non-coding RNAs or RNA modifications are only acceptable for the journal when including: 

  • data on the molecular epigenetic regulation of the expression of non-coding RNA (or its modifying enzymes) or
  • insights on the mechanism of action of the non-coding RNA on the chromatin and/or functioning of the DNA or
  • insights in mitotic stability of the RNA-induced effect

Editorial Policy Regarding Submissions Focusing on In silico research

Manuscripts reporting on straightforward bioinformatic analyses of publicly accessible databases only, cannot be considered for publication in Epigenetics Communications, unless the manuscript presents:

  • new, convincingly-described, scientific insights which will impact the field and/or
  • additional insights into underlying biological mechanisms (“wet-lab” validations) and/or
  • validations of findings in a replication cohort

Aims and scope

Epigenetics Communications covers the broad spectrum of epigenetic science from basic research to technological, molecular and preclinical innovations, as well as their theoretical, ethical and societal dimensions. Epigenetics Communications is an open-access journal devoted to the study and problematization of epigenetic principles and mechanisms in basic and translational research settings.

The editorial process of Epigenetics Communications focusses on the technical quality of the manuscript including the robustness and validity of the research, from methodological, analytical, statistical and ethical perspectives. Novelty and potential impact are not a pre-requisite for the evaluation.

It is also a forum for interdisciplinary debates around epigenetics, as well as for the investigation of its societal dimensions. In support of open science initiatives, the journal will have a level 4 data policy requiring data be made fully publicly available. The journal publishes studies related to the following topics:
 

  • Molecular Epigenetics (Histone Modifications; DNA Methylation; DNA Demethylation)
  • Nuclear Organization
  • Mitotic & Meiotic Heritability
  •  Epigenetic Drugs
  • Epigenetic Technologies
  • Epigenetic Bioengineering
  • Network Epigenetics
  • Computational Epigenomics
  • Single Cell Epigenetics
  • Epigenetic Toxicology
  •  Epigenetic studies using Model Organisms (Vertebrates; Invertebrates; Plants; Unicellular systems)
  • Epigenetics, Ethics and Society


Submissions describing clinical applications should first be considered for submission to the sister journal, 
Clinical Epigenetics.

This innovative journal will also act as a forum to showcase and discuss alternative conclusions/interpretations of well-established epigenetic phenomena. These can be based either on the (re-)analyses of published and/or new data, or on the findings and results of epigenetic research in interaction with other disciplines. As such, we welcome 'systematic’ and ‘critical’ studies, be them positive (expected) or negative (non-expected) with respect to their outcomes.

Affiliated with

  • Epigenetics Communications is affiliated with the International Society for Molecular and Clinical Epigenetics (isMOCLEP). isMOCLEP is open to all those interested in the wide spectrum of epigenetic research, from molecular to clinical aspects. isMOCLEP community welcomes academic researchers, early career scientists, companies, policy makers, and beyond.

Annual Journal Metrics

Speed 2024
Submission to first editorial decision (median days): 10
Submission to acceptance (median days): 115

Usage 2024
Downloads: 41,008
Altmetric mentions: 15