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Table 1 Summary statistics of maternal urinary biomarkers (n = 72)

From: Gestational exposure to environmental chemicals and epigenetic alterations in the placenta and cord blood mononuclear cells

Chemical biomarker

LOD

% < LOD

Median (IQR)**

1-Hydroxynaphthalene*

0.05

4.0

142.1 (74.5-303.3)

2-Hydroxynaphthalene*

0.05

0.0

4380.7 (2490.5-8461.6)

2-Hydroxyfluorene*

0.01

1.3

123.9 (73.4-232.7)

1-Hydroxyphenanthrene*

0.01

0.0

121.9 (74.7-194.4)

2,3-Hydroxyphenanthrene*

0.02

0.0

101.2 (68.9-154.4)

4-Hydroxyphenanthrene*

0.01

12.0

14.3 (4.2–20.4)

9-Hydroxyphenanthrene*

0.01

8.0

17.7 (10.4–33.3)

1-Hydroxypyrene*

0.01

1.3

120.3 (70.9–173.0)

Monoethyl phthalate

1.2

0

13.1 (4.9–47.2)

Mono-n-butyl phthalate

0.4

5.3

3.8 (1.9–12.8)

Mono-isobutyl phthalate

0.8

21.3

3.0 (0.9–11.5)

Monobenzyl phthalate

0.3

8.0

1.7 (0.9–7.6)

Mono-3-carboxypropyl phthalate

0.4

41.3

0.6 (< LOD-1.8)

Mono-2-ethyl-5-carboxypentyl phthalateb

0.4

0

112 (43.3-269.5)

Mono-2-ethyl-5-hydroxyhexyl phthalateb

0.4

0

69.7 (26.6–198.0)

Mono-2-ethyl-5-oxohexyl phthalateb

0.2

0

61.0 (16.35–160.0)

Mono-2-ethylhexyl phthalateb

0.8

4.0

45.3 (10.9-112.5)

Mono-isononyl phthalatea

0.9

93.3

< LOD

Monooxononyl phthalate

0.4

21.3

1 (0.5–2.9)

Mono carboxyisooctyl phthalate

0.3

10.7

1 (0.3–3.3)

Mono carboxyisononyl phthalate

0.2

0

3.3 (1.5–10.5)

Mono-2-ethyl-5-carboxypentyl terephthalate

0.2

0

20.1 (5.9–59.3)

Mono-2-ethyl-5-hydroxyhexyl terephthalate

0.4

33.3

1.4 (< LOD-6.3)

Cyclohexane-1,2-dicarboxylic acid, monocarboxy isooctyl ester

0.5

80

< LOD

Cyclohexane-1,2-dicarboxylic acid, monohydroxy isononyl ester

0.4

64

< LOD (< LOD-0.7)

2,4-Dichlorophenol

0.1

9.3

0.5 (0.2–1.1)

2,5-Dichlorophenol

0.1

6.7

1.2 (0.5–6.8)

Benzophenone-3

0.4

4.0

6.7 (2.4–25.7)

Bisphenol A

0.2

4.0

1.0 (0.5-2.0)

Bisphenol F

0.2

56

< LOD (< LOD-0.5)

Bisphenol S

0.1

24

0.2 (0.1–0.7)

Methyl parabenb

1.0

0

376.7 (68.5-1214.6)

Ethyl parabenb

1.0

26.7

2.1 (< LOD-16.2)

Propyl parabenb

0.1

1.3

21.1 (3.9–84.1)

Butyl paraben

0.1

72

< LOD

Triclocarban

0.1

52

< LOD (< LOD-0.6)

Triclosan

1.7

52

< LOD(< LOD-4.2)

  1. aExcluded in further analysis due to relatively low detection frequencies
  2. bExcluded due to relatively high concentrations that are likely due to use of medical tubing/medications/wipes at delivery
  3. *Unit of concentration for PAH biomarkers is nanogram/gram creatinine (ng/g creatinine); concentration unit for all other biomarkers is microgram/gram creatinine (µg/g creatinine)
  4. **Biomarker concentrations standardized with urine creatinine concentration