Fig. 2
From: Uncovering the significance of CBX3 as an up-and-coming biomarker in cardio-vascular health
Schematic representation of CBX3 roles in cardiovascular disease. The involvement of CBX3 brought by Notch3 interaction in controlling VSMC defines the contributions made by prolifera- tion, migration and formation of neointima to pathogenesis of vascular injuries and diseases. CBX3 is involved in the regulation of angiogenesis and could have an impact on restenosis after angioplasty. Ep- igenetic modifications shared by CBX3 also involve vascular remodeling and homeostasis as well as regulation of angiogenesis and atherosclerosis